INT272346

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Context Info
Confidence 0.36
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.96
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA processing (Adar) nucleolus (Adar) RNA binding (Adar)
nucleus (Adar) intracellular (Adar) DNA binding (Adar)
Anatomy Link Frequency
neurons 2
ADAR 2
Adar (Mus musculus)
Pain Link Frequency Relevance Heat
adenocard 15 39.28 Quite Low
tetrodotoxin 1 27.12 Quite Low
antagonist 3 25.12 Quite Low
Serotonin 14 5.00 Very Low Very Low Very Low
Glutamate 13 5.00 Very Low Very Low Very Low
ischemia 9 5.00 Very Low Very Low Very Low
Central nervous system 8 5.00 Very Low Very Low Very Low
Glutamate receptor 6 5.00 Very Low Very Low Very Low
Action potential 5 5.00 Very Low Very Low Very Low
potassium channel 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thiamine Deficiency 62 99.88 Very High Very High Very High
Targeted Disruption 9 87.68 High High
Death 18 5.00 Very Low Very Low Very Low
Motor Neuron Diseases 17 5.00 Very Low Very Low Very Low
Stress 13 5.00 Very Low Very Low Very Low
Disease 10 5.00 Very Low Very Low Very Low
Epilepsy 9 5.00 Very Low Very Low Very Low
Cancer 9 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 8 5.00 Very Low Very Low Very Low
Schizophrenia 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Regulation of ADAR activity by alternative splicing
Regulation (Regulation) of Transcription (activity) of ADAR in ADAR
1) Confidence 0.36 Published 2009 Journal Mol Brain Section Body Doc Link PMC2694175 Disease Relevance 0.09 Pain Relevance 0
A real-time PCR study showed that TD down-regulated mRNA levels of ADAR2, but not that of ADAR1 in cortical neurons (Figure 4E).
Regulation (regulated) of Transcription (levels) of ADAR1 in neurons associated with thiamine deficiency
2) Confidence 0.30 Published 2010 Journal Mol Neurodegener Section Body Doc Link PMC3006372 Disease Relevance 0.87 Pain Relevance 0

General Comments

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