INT272354

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Context Info
Confidence 0.49
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.31
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA processing (Adar) nucleolus (Adar) RNA binding (Adar)
nucleus (Adar) intracellular (Adar) DNA binding (Adar)
Anatomy Link Frequency
ADAR 2
Adar (Mus musculus)
Pain Link Frequency Relevance Heat
Serotonin 28 73.68 Quite High
Glutamate 20 72.36 Quite High
depression 6 64.04 Quite High
Central nervous system 4 63.24 Quite High
fluoxetine 4 32.04 Quite Low
Glutamate receptor 6 24.28 Low Low
adenocard 22 5.00 Very Low Very Low Very Low
ischemia 10 5.00 Very Low Very Low Very Low
Action potential 10 5.00 Very Low Very Low Very Low
potassium channel 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Schizophrenia 10 65.20 Quite High
Epilepsy 18 64.44 Quite High
Depression 6 64.04 Quite High
Disease 8 62.04 Quite High
Attention Deficit Hyperactivity Disorder 2 56.76 Quite High
Mental Disorders 4 49.60 Quite Low
Neurodegenerative Disease 4 48.32 Quite Low
Stress 4 34.60 Quite Low
Sprains And Strains 6 27.76 Quite Low
Motor Neuron Diseases 28 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This review attempts to provide an insight to existing models of explanation – regulation of ADAR expression and activity by self-editing, alternative splicing and cross-talk among ADAR family members; developmental and activity-dependent regulation of A-to-I editing through environmental cues.
Regulation (regulation) of Gene_expression (expression) of ADAR in ADAR
1) Confidence 0.49 Published 2009 Journal Mol Brain Section Body Doc Link PMC2694175 Disease Relevance 0.31 Pain Relevance 0.14
In addition, expression of ADAR1 and ADAR2 does not correspond with editing frequencies of specific target sites in the 5-HT2CR mRNA.
Neg (not) Regulation (correspond) of Gene_expression (expression) of ADAR1
2) Confidence 0.36 Published 2009 Journal Mol Brain Section Body Doc Link PMC2694175 Disease Relevance 0 Pain Relevance 0

General Comments

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