INT272361

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Context Info
Confidence 0.40
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.37
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA processing (Adar) nucleolus (Adar) RNA binding (Adar)
nucleus (Adar) intracellular (Adar) DNA binding (Adar)
Anatomy Link Frequency
ADAR 1
Adar (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate receptor 3 28.72 Quite Low
Serotonin 14 23.76 Low Low
adenocard 11 5.00 Very Low Very Low Very Low
Glutamate 10 5.00 Very Low Very Low Very Low
ischemia 5 5.00 Very Low Very Low Very Low
Action potential 5 5.00 Very Low Very Low Very Low
potassium channel 4 5.00 Very Low Very Low Very Low
depression 3 5.00 Very Low Very Low Very Low
hyperexcitability 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 7 99.70 Very High Very High Very High
Epilepsy 9 93.28 High High
Motor Neuron Diseases 14 5.00 Very Low Very Low Very Low
Cancer 9 5.00 Very Low Very Low Very Low
Schizophrenia 5 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low
Glioblastoma 5 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 5 5.00 Very Low Very Low Very Low
Convulsion 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Editing of mRNA transcripts by ADAR enzymes is critical for normal life and development, as observed from the knockout mice that are deficient in either ADAR1 or ADAR2.
Negative_regulation (deficient) of ADAR1 in ADAR associated with targeted disruption
1) Confidence 0.40 Published 2009 Journal Mol Brain Section Body Doc Link PMC2694175 Disease Relevance 0.37 Pain Relevance 0

General Comments

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