INT272365

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Adarb1) endoplasmic reticulum (GRIA1) intracellular (Adarb1)
signal transduction (GRIA1) RNA binding (Adarb1) nucleolus (Adarb1)
Adarb1 (Mus musculus)
GRIA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Serotonin 14 89.44 High High
Glutamate receptor 3 87.32 High High
adenocard 11 5.00 Very Low Very Low Very Low
Glutamate 10 5.00 Very Low Very Low Very Low
ischemia 5 5.00 Very Low Very Low Very Low
Action potential 5 5.00 Very Low Very Low Very Low
potassium channel 4 5.00 Very Low Very Low Very Low
depression 3 5.00 Very Low Very Low Very Low
hyperexcitability 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 2 93.00 High High
Epilepsy 9 60.84 Quite High
Targeted Disruption 7 52.08 Quite High
Motor Neuron Diseases 14 5.00 Very Low Very Low Very Low
Cancer 9 5.00 Very Low Very Low Very Low
Schizophrenia 5 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low
Glioblastoma 5 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 5 5.00 Very Low Very Low Very Low
Convulsion 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overexpression of ADAR2 in NPCs results in Q/R editing and expression of calcium-impermeable AMPA receptors, which prevents AMPA-mediated differentiation, suggesting a physiological role for the Q/R editing process and the importance of unedited AMPA receptor subunits in neurogenesis [46].
Gene_expression (Overexpression) of ADAR2 Positive_regulation (results) of Gene_expression (expression) of AMPA associated with neurodegenerative disease
1) Confidence 0.00 Published 2009 Journal Mol Brain Section Body Doc Link PMC2694175 Disease Relevance 0.26 Pain Relevance 0.09

General Comments

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