INT272417

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MAPK1) mitochondrion (MAPK1) Golgi apparatus (MAPK1)
DNA binding (MAPK1) protein complex (MAPK1) response to stress (MAPK1)
PROK1 (Homo sapiens)
MAPK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 1 96.08 Very High Very High Very High
antagonist 2 27.24 Quite Low
Inflammation 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Intracerebroventricular 1 5.00 Very Low Very Low Very Low
IPN 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bordatella Infection 1 79.96 Quite High
Cancer 7 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Hypoxia 5 5.00 Very Low Very Low Very Low
Reprotox - General 1 5 5.00 Very Low Very Low Very Low
Hyperplasia 4 5.00 Very Low Very Low Very Low
Nociception 4 5.00 Very Low Very Low Very Low
Polycystic Ovary Syndrome 4 5.00 Very Low Very Low Very Low
Hematological Disease 4 5.00 Very Low Very Low Very Low
Kallmann Syndrome 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of ERK 1 and 2 through PK1–PKR1 binding has been demonstrated, by use of specific inhibitors, to be important in PK1-induced proliferation and migration of ACE cells [17].


PK1 Binding (binding) of Positive_regulation (Activation) of ERK 1 and 2
1) Confidence 0.01 Published 2007 Journal Trends in Endocrinology and Metabolism Section Body Doc Link PMC2694302 Disease Relevance 0.08 Pain Relevance 0.05

General Comments

This test has worked.

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