INT272427

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.33
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ARAF) protein modification process (ARAF) mitochondrion (ARAF)
cellular_component (ARAF)
Anatomy Link Frequency
reproductive tract 2
ARAF (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 7 99.16 Very High Very High Very High
Neuropathic pain 1 43.80 Quite Low
Migraine 1 42.96 Quite Low
Inflammation 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Intracerebroventricular 1 5.00 Very Low Very Low Very Low
IPN 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hematological Disease 4 96.24 Very High Very High Very High
Cancer 19 90.08 High High
Testicular Cancer 1 74.96 Quite High
Seminoma 1 72.80 Quite High
Hypoxia 5 69.40 Quite High
Apoptosis 2 67.12 Quite High
Myelodysplastic Syndromes 1 59.12 Quite High
Hyperplasia 4 59.04 Quite High
Leukemia 1 58.04 Quite High
Reprotox - General 1 5 53.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, cells express up to three Raf types (i.e., A-, B- and c-Raf), which are affected differently by upstream targets, thereby adding a further level of complexity to MAPK-mediated signaling [13,14].
Regulation (affected) of Gene_expression (express) of Raf
1) Confidence 0.02 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2918577 Disease Relevance 0.49 Pain Relevance 0.12
Role of PKs in pathologies of the reproductive tract
Regulation (pathologies) of Gene_expression (Role) of PKs in reproductive tract
2) Confidence 0.02 Published 2007 Journal Trends in Endocrinology and Metabolism Section Body Doc Link PMC2694302 Disease Relevance 0.84 Pain Relevance 0

General Comments

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