INT272487

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Context Info
Confidence 0.54
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.48
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA processing (Mbnl1) RNA binding (Mbnl1) nucleus (Mbnl1)
cytoplasm (Mbnl1)
Mbnl1 (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 2 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myotonic Dystrophy 8 75.00 Quite High
Cataract 4 67.24 Quite High
Arrhythmias 2 Under Development 1 66.80 Quite High
Hypopituitarism 11 65.68 Quite High
Frailty 3 65.28 Quite High
Disease 13 5.00 Very Low Very Low Very Low
Targeted Disruption 8 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Arrhythmia Under Development 2 5.00 Very Low Very Low Very Low
Ataxia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CUG-BP1 and MBNL1 proteins act antagonistically in exon selection in several pre-mRNA transcripts, thus MBNL1 sequestration and increase in nuclear activity of CUG-BP1 both act synergistically to missplice defined transcripts.
Transcription (transcripts) of MBNL1
1) Confidence 0.54 Published 2008 Journal Current Genomics Section Abstract Doc Link PMC2694559 Disease Relevance 0.48 Pain Relevance 0

General Comments

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