INT272520

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Dmpk, Nkx2-5) nucleus (Dmpk, Nkx2-5) cell differentiation (Nkx2-5)
mitochondrion (Dmpk) endoplasmic reticulum (Dmpk) DNA binding (Nkx2-5)
Anatomy Link Frequency
skeletal muscle 3
Dmpk (Mus musculus)
Nkx2-5 (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 2 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 2 99.32 Very High Very High Very High
Targeted Disruption 8 98.40 Very High Very High Very High
Muscular Dystrophy 1 92.00 High High
Disease 13 85.80 High High
Hypopituitarism 11 56.36 Quite High
Myotonic Dystrophy 8 50.00 Quite Low
Cataract 4 5.00 Very Low Very Low Very Low
Frailty 3 5.00 Very Low Very Low Very Low
Arrhythmia Under Development 2 5.00 Very Low Very Low Very Low
Ataxia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, overexpression of DMPK 3' UTR mRNA in mouse skeletal muscle also induced transcriptional activation of Nkx2-5 and its targets.
Gene_expression (overexpression) of DMPK in skeletal muscle Positive_regulation (induced) of Positive_regulation (activation) of Nkx2-5 in skeletal muscle
1) Confidence 0.02 Published 2008 Journal Current Genomics Section Body Doc Link PMC2694559 Disease Relevance 0.43 Pain Relevance 0

General Comments

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