INT272530

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.98
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

NARFL (Homo sapiens)
Pain Link Frequency Relevance Heat
beta blocker 13 87.72 High High
dexamethasone 1 56.16 Quite High
metalloproteinase 11 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
agonist 7 5.00 Very Low Very Low Very Low
headache 5 5.00 Very Low Very Low Very Low
eye pain 4 5.00 Very Low Very Low Very Low
Angina 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ocular Hypertension 385 100.00 Very High Very High Very High
Hypotension 30 100.00 Very High Very High Very High
Open-angle Glaucoma 12 99.88 Very High Very High Very High
Glaucoma 91 98.92 Very High Very High Very High
Stress 1 55.20 Quite High
Macular Edema 21 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 17 5.00 Very Low Very Low Very Low
Uveitis 16 5.00 Very Low Very Low Very Low
Conjunctivitis 13 5.00 Very Low Very Low Very Low
Cataract 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A family history of glaucoma should be elicited in all patients, as this may be a predisposition to higher IOP rise following IVTA.
Negative_regulation (predisposition) of Localization (rise) of IOP associated with glaucoma and ocular hypertension
1) Confidence 0.09 Published 2008 Journal The Open Ophthalmology Journal Section Body Doc Link PMC2694598 Disease Relevance 1.11 Pain Relevance 0.03
Patients with OH or OAG were washed out of their usual ocular hypotensive medications and then those with a baseline IOP ?
Negative_regulation (washed) of Localization (baseline) of IOP associated with hypotension, open-angle glaucoma and ocular hypertension
2) Confidence 0.09 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2993108 Disease Relevance 1.34 Pain Relevance 0.04
Authors commented that 4 trials evaluating latanoprost vs timolol, were not included which may have lead to a lower IOP decrease for latanoprost compared with the meta-analysis by van der Valk.84
Negative_regulation (lower) of Localization (decrease) of IOP associated with ocular hypertension
3) Confidence 0.03 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2915861 Disease Relevance 0.53 Pain Relevance 0

General Comments

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