INT272605

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Context Info
Confidence 0.36
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.41
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Dlg4, Nsf) cytoplasm (Dlg4, Nsf) transport (Nsf)
vesicle-mediated transport (Nsf) structural molecule activity (Dlg4) ATPase activity (Nsf)
Anatomy Link Frequency
synaptic vesicle 2
Dlg4 (Mus musculus)
Nsf (Mus musculus)
Pain Link Frequency Relevance Heat
nMDA receptor 6 81.92 Quite High
Glutamate receptor 18 54.28 Quite High
Neurotransmitter 8 5.00 Very Low Very Low Very Low
long-term potentiation 6 5.00 Very Low Very Low Very Low
Glutamate 6 5.00 Very Low Very Low Very Low
Action potential 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
potassium channel 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 22 78.88 Quite High
Aids-related Complex 4 75.12 Quite High
Schizophrenia 26 50.00 Quite Low
Mental Disorders 2 36.00 Quite Low
Cognitive Disorder 2 31.04 Quite Low
Targeted Disruption 12 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Intellectual Impairment 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As we show using reciprocal co-precipitation, the interaction of PSD-95 with N-ethylmaleimide sensitive fusion protein (NSF), a cytosolic ATPase, was required for intracellular membrane fusion, and this reinforces the idea of PSD-95 involvement in synaptic vesicle trafficking and AMPA surface-expression modulation (Luthi et al, 1999; Noel et al, 1999).
PSD-95 Binding (interaction) of NSF in synaptic vesicle
1) Confidence 0.36 Published 2009 Journal Mol Syst Biol Section Body Doc Link PMC2694677 Disease Relevance 0.21 Pain Relevance 0.07
As we show using reciprocal co-precipitation, the interaction of PSD-95 with N-ethylmaleimide sensitive fusion protein (NSF), a cytosolic ATPase, was required for intracellular membrane fusion, and this reinforces the idea of PSD-95 involvement in synaptic vesicle trafficking and AMPA surface-expression modulation (Luthi et al, 1999; Noel et al, 1999).
PSD-95 Binding (interaction) of N-ethylmaleimide sensitive fusion protein in synaptic vesicle
2) Confidence 0.36 Published 2009 Journal Mol Syst Biol Section Body Doc Link PMC2694677 Disease Relevance 0.20 Pain Relevance 0.07

General Comments

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