INT27261

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Context Info
Confidence 0.45
First Reported 1989
Last Reported 2008
Negated 0
Speculated 0
Reported most in Title
Documents 7
Total Number 7
Disease Relevance 2.80
Pain Relevance 5.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Calca) aging (Calca) extracellular region (Calca)
nucleus (Calca) intracellular (Calca) cytoplasm (Calca)
Anatomy Link Frequency
spinal 2
plasma 2
muscle 2
nucleus 2
preoptic area 2
Calca (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 60 100.00 Very High Very High Very High
Neurotransmitter 30 100.00 Very High Very High Very High
Calcitonin gene-related peptide 22 100.00 Very High Very High Very High
Pain 8 100.00 Very High Very High Very High
Enkephalin 6 100.00 Very High Very High Very High
substance P 5 100.00 Very High Very High Very High
epidural 5 100.00 Very High Very High Very High
Serotonin 4 100.00 Very High Very High Very High
Analgesic 3 100.00 Very High Very High Very High
analgesia 2 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Headache 28 100.00 Very High Very High Very High
Cluster Headache 1 99.76 Very High Very High Very High
Disease 1 97.20 Very High Very High Very High
Ganglion Cysts 18 96.16 Very High Very High Very High
Migraine With Aura 4 89.04 High High
Epilepsy 3 83.68 Quite High
Neurogenic Inflammation 2 80.36 Quite High
Pain 5 69.56 Quite High
Targeted Disruption 1 67.76 Quite High
Pressure Volume 2 Under Development 1 64.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We studied the effect of nitroglycerin on the innervated area of calcitonin gene-related peptide (CGRP) and serotonin-immunoreactive afferents to the superficial laminae of the spinal portion of trigeminal nucleus caudalis, and its modulation by estrogen.
Regulation (effect) of Regulation (modulation) of calcitonin gene-related peptide in spinal associated with serotonin and calcitonin gene-related peptide
1) Confidence 0.45 Published 2002 Journal Eur. J. Neurosci. Section Abstract Doc Link 12081660 Disease Relevance 0.18 Pain Relevance 0.48
Time-course analysis of changes in calcitonin gene-related peptide-and methionine-enkephalin-immunoreactivity in the female rat preoptic area after estrogen treatment.
Regulation (changes) of Regulation (immunoreactivity) of calcitonin in preoptic area associated with enkephalin and calcitonin gene-related peptide
2) Confidence 0.27 Published 1993 Journal Neuroscience Section Title Doc Link 8232897 Disease Relevance 0 Pain Relevance 0.48
The effects of epidural analgesia on plasma calcitonin gene-related peptide (CGRP) values during and after hysterectomy were investigated in 14 healthy patients.
Regulation (effects) of Regulation (values) of CGRP in plasma associated with epidural, calcitonin gene-related peptide and analgesia
3) Confidence 0.26 Published 1989 Journal Acta Anaesthesiol Scand Section Abstract Doc Link 2588998 Disease Relevance 0.06 Pain Relevance 0.58
We used various agents which are known to affect muscle fibre acetylcholine receptor regulation, namely, CGRP, tetrodotoxin, and KCl and obtained results which demonstrate the full effectiveness of this way of application.
Regulation (affect) of Regulation (regulation) of CGRP in muscle associated with tetrodotoxin
4) Confidence 0.24 Published 2001 Journal J. Neurosci. Methods Section Abstract Doc Link 11325430 Disease Relevance 0 Pain Relevance 0.10
Alterations in neurokinin A-, substance P- and calcitonin gene-related peptide immunoreactivities in the caudal trigeminal nucleus of the rat following electrical stimulation of the trigeminal ganglion.
Regulation (Alterations) of Regulation (immunoreactivities) of gene-related peptide in nucleus associated with ganglion cysts, nociceptor, trigeminal ganglion, calcitonin gene-related peptide and substance p
5) Confidence 0.24 Published 1999 Journal Neurosci. Lett. Section Title Doc Link 10081978 Disease Relevance 0.64 Pain Relevance 0.89
The regulated release of neurotransmitters, such as glutamate and CGRP, is controlled by voltage-dependent calcium channels, including P/Q- type channels.
Regulation (controlled) of Regulation (regulated) of CGRP associated with glutamate, neurotransmitter and calcium channel
6) Confidence 0.23 Published 2008 Journal Mol Pain Section Body Doc Link PMC2359740 Disease Relevance 1.30 Pain Relevance 1.62
Effects of salmon calcitonin on patients with atypical (idiopathic) facial pain: a randomized controlled trial.
Regulation (controlled) of Regulation (Effects) of calcitonin associated with pain, analgesic and headache
7) Confidence 0.05 Published 1996 Journal J Orofac Pain Section Title Doc Link 9161235 Disease Relevance 0.62 Pain Relevance 0.93

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