INT272619

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Context Info
Confidence 0.10
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.91
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lyase activity (GAD1) nucleus (CEBPZ) plasma membrane (GAD1)
intracellular (GAD1) DNA binding (CEBPZ)
Anatomy Link Frequency
basal ganglia 1
GAD1 (Homo sapiens)
CEBPZ (Homo sapiens)
Pain Link Frequency Relevance Heat
positron emission tomography 18 99.30 Very High Very High Very High
imagery 25 80.48 Quite High
Thalamus 12 75.80 Quite High
amygdala 49 55.76 Quite High
insula 19 54.32 Quite High
fluoxetine 2 42.08 Quite Low
Anterior cingulate cortex 21 25.92 Quite Low
Hippocampus 15 5.00 Very Low Very Low Very Low
medulla 7 5.00 Very Low Very Low Very Low
Anterior cingulate 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Generalized Anxiety Disorder 9 100.00 Very High Very High Very High
Anxiety Disorder 107 98.96 Very High Very High Very High
Stress 2 87.48 High High
Urological Neuroanatomy 12 76.72 Quite High
Panic Disorder 36 68.56 Quite High
Phobia 59 55.52 Quite High
Cognitive Disorder 8 40.96 Quite Low
Agoraphobia 3 5.00 Very Low Very Low Very Low
Depression 3 5.00 Very Low Very Low Very Low
Unconsciousness 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Positron emission tomography investigations revealed increased metabolism in the occipital, temporal, frontal, and cerebellar region and a lower CBF in the basal ganglia of patients with GAD after presentation of an anxiety-inducing task (Wu et al. 1991).
GAD Binding (metabolism) of CBF in basal ganglia associated with generalized anxiety disorder, anxiety disorder and positron emission tomography
1) Confidence 0.10 Published 2008 Journal J Neural Transm Section Body Doc Link PMC2694920 Disease Relevance 0.91 Pain Relevance 0.25

General Comments

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