INT27266
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Studies focused on changes in POMC gene expression (mRNA quantitation) and post-translational processing. | |||||||||||||||
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In that, GABAergic neurotransmission appear to be involved in the regulation of the hypothalamic POMC gene expression induced by supraspinal morphine administration. | |||||||||||||||
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POMC gene expression in the CNS is believed to be controlled by distinct cis-acting regulatory sequences. | |||||||||||||||
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Therefore, the influence of the TIQ salsolinol (SAL) on the pro-opiomelanocortin (POMC) gene expression was investigated using the ArT-20 mouse anterior pituitary tumor cell line. | |||||||||||||||
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In addition, the proopiomelanocortin (POMC) gene expression was significantly down regulated in serum-reduced medium and was normalized again after further cultivation in a 10% serum containing medium. | |||||||||||||||
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However, i.t. glutamate injection did not affect the hypothalamic POMC gene expression at all time points. | |||||||||||||||
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Similarly, morphine had no effect on ACTH production by dispersed rat pituitary cells in monolayer culture in response to 90- and 180-min incubations with 5 nM CRH. | |||||||||||||||
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We studied the effects of supraspinally administered morphine on the expression of the hypothalamic pro-opiomelanocortin (POMC) gene and beta-endorphin. | |||||||||||||||
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Possible involvement of the hypothalamic pro-opiomelanocortin gene and beta-endorphin expression on acute morphine withdrawal development. | |||||||||||||||
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We studied the effects of supraspinally administered morphine on the expression of the hypothalamic pro-opiomelanocortin (POMC) gene and beta-endorphin. | |||||||||||||||
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The existing information indicating the importance of beta-endorphin neurotransmission in mediating the reward pathways of nicotine and THC, is thus far circumstantial. | |||||||||||||||
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Effect of S(-)- and R(+)-salsolinol on the POMC gene expression and ACTH release of an anterior pituitary cell line. | |||||||||||||||
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The role of POMC-derived peptides of pituitary origin in the modulation of brain POMC mRNA expression and opioid receptor binding was investigated using a line of transgenic mice that express a fusion gene composed of the pituitary expression-specific promoter region of the POMC gene driving the herpes simplex viral-1 thymidine kinase (TK). | |||||||||||||||
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We studied the effects of supraspinally administered morphine on the expression of the hypothalamic pro-opiomelanocortin (POMC) gene and beta-endorphin. | |||||||||||||||
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Therefore, the influence of the TIQ salsolinol (SAL) on the pro-opiomelanocortin (POMC) gene expression was investigated using the ArT-20 mouse anterior pituitary tumor cell line. | |||||||||||||||
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In addition, the proopiomelanocortin (POMC) gene expression was significantly down regulated in serum-reduced medium and was normalized again after further cultivation in a 10% serum containing medium. | |||||||||||||||
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Results indicate that the ACTH levels and IFN-alpha gene expression were higher in the conditioned animals than in the controls. | |||||||||||||||
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This implies that hypothalamic TRH release is controlled by POMC and AgRP neurones. | |||||||||||||||
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Neuroendocrine targets for POMC products in the PVN | |||||||||||||||
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Hypothalamic expression levels of peptides known to be involved in appetite regulation, such as NPY, POMC, and AGRP, are changed upon food deprivation, and neurons expressing these molecules are essential components in the control of energy homeostasis [8]. | |||||||||||||||
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General Comments
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