INT272755

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.13
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (DBI) signal transduction (Ptger2) transport (DBI)
plasma membrane (Ptger2) signal transducer activity (Ptger2)
DBI (Homo sapiens)
Ptger2 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 100 72.76 Quite High
Inflammation 6 65.36 Quite High
withdrawal 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
cerebral cortex 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 14 98.68 Very High Very High Very High
Endometriosis (extended) 16 82.76 Quite High
Reprotox - General 1 4 81.52 Quite High
INFLAMMATION 6 65.36 Quite High
Adenocarcinoma 18 43.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We and others’ have shown that PGE2–EP receptor interaction can down regulate the expression of tumour suppressor genes (Sales et al., 2004c), increase cellular growth, migration and invasiveness (Sheng et al., 2001) and promote angiogenesis in in vitro and in vivo model systems (Watanabe et al., 2000; Sonoshita et al., 2001; Seno et al., 2002; Buchanan et al., 2003; Fujino et al., 2003; Sales et al., 2004a).
EP Binding (interaction) of PGE2 associated with cancer
1) Confidence 0.00 Published 2008 Journal Molecular and Cellular Endocrinology Section Body Doc Link PMC2694994 Disease Relevance 0.57 Pain Relevance 0.16
We and others’ have shown that PGE2–EP receptor interaction can down regulate the expression of tumour suppressor genes (Sales et al., 2004c), increase cellular growth, migration and invasiveness (Sheng et al., 2001) and promote angiogenesis in in vitro and in vivo model systems (Watanabe et al., 2000; Sonoshita et al., 2001; Seno et al., 2002; Buchanan et al., 2003; Fujino et al., 2003; Sales et al., 2004a).
EP Binding (interaction) of PGE2 associated with cancer
2) Confidence 0.00 Published 2008 Journal Molecular and Cellular Endocrinology Section Body Doc Link PMC2694994 Disease Relevance 0.57 Pain Relevance 0.16

General Comments

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