INT272873

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Context Info
Confidence 0.05
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.57
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Epas1) signal transduction (Epas1) mitochondrion organization (Epas1)
nucleus (Epas1) DNA binding (Epas1) transcription factor binding (Epas1)
Anatomy Link Frequency
epithelial cell 1
Epas1 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 19 83.40 Quite High
Inflammation 100 69.56 Quite High
Multiple sclerosis 2 11.52 Low Low
cytokine 25 5.00 Very Low Very Low Very Low
chemokine 20 5.00 Very Low Very Low Very Low
metalloproteinase 19 5.00 Very Low Very Low Very Low
Bioavailability 11 5.00 Very Low Very Low Very Low
corticosteroid 5 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
Infliximab 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 1 100.00 Very High Very High Very High
Bronchitis 9 99.96 Very High Very High Very High
Apoptosis 7 98.90 Very High Very High Very High
Emphysema 22 98.16 Very High Very High Very High
Death 2 96.76 Very High Very High Very High
Pulmonary Disease 144 94.68 High High
Metastasis 1 81.44 Quite High
Cancer 5 80.56 Quite High
Asthma 12 73.72 Quite High
Nicotine Addiction 49 70.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, in patients with emphysema for example, inhibitors of apoptosis are needed whereas in contrast to chronic bronchitis, expression of hypoxia-inducible factor, VEGF, and VEGFR2 may be stimulated to overcome endothelial and epithelial cell death and improve vascular restoration (Voelkel and Coll 2003).
Gene_expression (expression) of hypoxia-inducible factor in epithelial cell associated with emphysema, hypoxia, bronchitis, apoptosis and death
1) Confidence 0.05 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2695202 Disease Relevance 1.57 Pain Relevance 0.13

General Comments

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