INT272876

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Context Info
Confidence 0.18
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.57
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Sod1) aging (Sod1) peroxisome (Sod1)
intracellular (Sod1) protein complex (Sod1) cytoplasm (Sod1)
Anatomy Link Frequency
alveolar macrophages 2
Sod1 (Mus musculus)
Pain Link Frequency Relevance Heat
Bioavailability 11 59.92 Quite High
Inflammation 100 26.88 Quite Low
cytokine 25 5.00 Very Low Very Low Very Low
chemokine 20 5.00 Very Low Very Low Very Low
antagonist 19 5.00 Very Low Very Low Very Low
metalloproteinase 19 5.00 Very Low Very Low Very Low
corticosteroid 5 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
Infliximab 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nicotine Addiction 49 99.20 Very High Very High Very High
Tumor Necrosis Factor Receptor-associated Periodic Syndrome 2 83.28 Quite High
Adhesions 5 52.80 Quite High
Stress 23 50.64 Quite High
Pulmonary Disease 144 50.00 Quite Low
INFLAMMATION 106 26.88 Quite Low
Bronchitis 9 8.28 Low Low
Emphysema 22 5.00 Very Low Very Low Very Low
Disease 13 5.00 Very Low Very Low Very Low
Asthma 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The activities of CuZnSOD, glutathione-S-transferase and glutathione peroxidase (GP) are all decreased in alveolar macrophages from elderly smokers (Gilks et al 1998).
Negative_regulation (decreased) of Localization (glutathione-S-transferase) of CuZnSOD in alveolar macrophages associated with nicotine addiction
1) Confidence 0.18 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2695202 Disease Relevance 0.57 Pain Relevance 0.03

General Comments

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