INT272890

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Context Info
Confidence 0.19
First Reported 2007
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.33
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Smad7) plasma membrane (Smad7) nucleus (Smad7)
intracellular (Smad7) protein complex (Smad7) cytoplasm (Smad7)
Smad7 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 100 99.56 Very High Very High Very High
cytokine 25 93.96 High High
metalloproteinase 19 84.28 Quite High
chemokine 20 5.00 Very Low Very Low Very Low
antagonist 19 5.00 Very Low Very Low Very Low
Bioavailability 11 5.00 Very Low Very Low Very Low
corticosteroid 5 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
Infliximab 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 106 99.56 Very High Very High Very High
Pulmonary Disease 144 99.48 Very High Very High Very High
Stress 23 98.60 Very High Very High Very High
Inflammatory Bowel Disease 2 90.00 High High
Emphysema 22 87.84 High High
Nicotine Addiction 49 83.76 Quite High
Wound Healing 1 80.68 Quite High
Pneumonia 4 33.28 Quite Low
Apoptosis 7 32.36 Quite Low
Disease 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
With regard to COPD, it is not known whether Smad7 downregulation is intrinsic or due to inflammation, oxidative stress, or other factors, and what the consequences are of differential expression of TGF?
Spec (whether) Regulation (intrinsic) of Spec (whether) Negative_regulation (downregulation) of Smad7 associated with stress, pulmonary disease and inflammation
1) Confidence 0.19 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2695202 Disease Relevance 1.33 Pain Relevance 0.29

General Comments

This test has worked.

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