INT272892

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Context Info
Confidence 0.25
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.10
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Bhr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Etanercept 2 98.66 Very High Very High Very High
Inflammation 132 91.68 High High
Infliximab 4 85.28 High High
metalloproteinase 19 82.32 Quite High
Bioavailability 11 69.60 Quite High
psoriasis 1 56.64 Quite High
spinal inflammation 1 55.40 Quite High
corticosteroid 19 50.44 Quite High
fibrosis 10 50.00 Quite Low
cytokine 27 41.72 Quite Low
Disease Link Frequency Relevance Heat
Disease 18 97.16 Very High Very High Very High
Asthma 48 96.16 Very High Very High Very High
INFLAMMATION 131 91.68 High High
Occupational Lung Diseases 18 89.20 High High
Muscle Disease 1 85.12 High High
Mucositis 7 66.92 Quite High
Pulmonary Disease 144 64.00 Quite High
Psoriasis 1 56.64 Quite High
Low Back Pain 1 55.40 Quite High
Rheumatoid Arthritis 5 54.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our study we observed a lack of correlation between the degree of BHR and subepithelial collagen III deposition.
Gene_expression (deposition) of BHR
1) Confidence 0.25 Published 2008 Journal Arch Immunol Ther Exp (Warsz) Section Body Doc Link PMC2805797 Disease Relevance 1.09 Pain Relevance 0.22
Other studies demonstrated that twice-weekly treatment with etanercept during 10 to 12 weeks improved the bronchial hyperresponsiveness (BHR, expressed as PC20), post-bronchodilator FEV1 and the quality of life of patients with refractory, severe asthmatic patients (Howarth et al 2005; Berry et al 2006).
Gene_expression (expressed) of BHR associated with asthma and etanercept
2) Confidence 0.08 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2695202 Disease Relevance 1.01 Pain Relevance 0.45

General Comments

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