INT2729

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.37
First Reported 1979
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 4.23
Pain Relevance 1.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (LTBR)
LTBR (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 8 99.36 Very High Very High Very High
Etanercept 9 98.68 Very High Very High Very High
Inflammation 2 98.56 Very High Very High Very High
spinal inflammation 2 96.88 Very High Very High Very High
Arthritis 1 95.76 Very High Very High Very High
rheumatoid arthritis 3 94.92 High High
Multiple sclerosis 1 81.92 Quite High
psoriasis 6 80.08 Quite High
withdrawal 2 75.00 Quite High
Infliximab 1 72.16 Quite High
Disease Link Frequency Relevance Heat
Necrosis 3 99.64 Very High Very High Very High
Cancer 3 99.46 Very High Very High Very High
Pain 8 99.36 Very High Very High Very High
Anxiety Disorder 10 99.10 Very High Very High Very High
INFLAMMATION 2 98.56 Very High Very High Very High
Low Back Pain 2 96.88 Very High Very High Very High
Seronegative Spondarthritis 1 95.76 Very High Very High Very High
Rheumatoid Arthritis 3 94.92 High High
Nociception 10 89.76 High High
Disease 3 89.52 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In (4), just after the noxious stimulation, there was a marked facilitation of RIII, Bi associated with increased pain sensation.
RIII Binding (associated) of associated with pain
1) Confidence 0.37 Published 1979 Journal Brain Res. Section Abstract Doc Link 509233 Disease Relevance 0.91 Pain Relevance 0.62
The startle response was elicited under conditions often used to record the RIII reflex.
RIII Binding (record) of associated with anxiety disorder
2) Confidence 0.37 Published 1992 Journal Pain Section Abstract Doc Link 1608645 Disease Relevance 1.10 Pain Relevance 0.15
Etanercept is a human fusion protein of the tumor necrosis factor receptor (TNFR) and the Fc region of IgG1 that binds to and presumably inhibits the pro-inflammatory and pro-proliferative activity of the tumor necrosis factor (TNF).
TNFR Binding (binds) of associated with necrosis, inflammation, cancer and etanercept
3) Confidence 0.17 Published 2004 Journal J Drugs Dermatol Section Abstract Doc Link 15176161 Disease Relevance 1.09 Pain Relevance 0.60
Tumour necrosis factor (TNF) ligand members and their associated TNF receptor (TNFR) superfamilies have many diverse physiological roles.
TNFR Binding (associated) of associated with necrosis and cancer
4) Confidence 0.08 Published 2008 Journal Neurochem. Res. Section Abstract Doc Link 17985235 Disease Relevance 1.13 Pain Relevance 0.33

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox