INT272946

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Context Info
Confidence 0.56
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.60
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Myod1) nucleus (Myod1) enzyme binding (Myod1)
DNA binding (Myod1) transcription factor binding (Myod1) cytoplasm (Myod1)
Anatomy Link Frequency
diaphragm 1
soleus 1
Myod1 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 6 15.76 Low Low
Inflammation 56 5.00 Very Low Very Low Very Low
cytokine 12 5.00 Very Low Very Low Very Low
corticosteroid 8 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Dismenorea 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 6 99.24 Very High Very High Very High
Atrophic Muscular Disorders 2 83.96 Quite High
Sprains And Strains 3 81.40 Quite High
Pulmonary Disease 196 76.88 Quite High
Muscular Atrophy 10 67.00 Quite High
Apoptosis 26 59.48 Quite High
Frailty 76 59.28 Quite High
Obesity 4 27.04 Quite Low
INFLAMMATION 58 5.00 Very Low Very Low Very Low
Fatigue 52 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In littermates of the double knockout, when one functional copy of Myf5 is present (Myf5nlacZ/+:Myod?
Localization (present) of Myod associated with targeted disruption
1) Confidence 0.56 Published 2010 Journal Bone Section Body Doc Link PMC2860222 Disease Relevance 0.18 Pain Relevance 0
Elevation of these proteins may thus contribute to the reduced abundance of MyoD protein but not mRNA in the soleus and diaphragm of emphysematous hamsters (Degens et al 2004), indicating MyoD breakdown rather than reduced transcription.
Localization (abundance) of MyoD in soleus
2) Confidence 0.26 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2695204 Disease Relevance 0.71 Pain Relevance 0
Elevation of these proteins may thus contribute to the reduced abundance of MyoD protein but not mRNA in the soleus and diaphragm of emphysematous hamsters (Degens et al 2004), indicating MyoD breakdown rather than reduced transcription.
Localization (abundance) of MyoD in diaphragm
3) Confidence 0.09 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2695204 Disease Relevance 0.71 Pain Relevance 0

General Comments

This test has worked.

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