INT272950

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Context Info
Confidence 0.41
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.70
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Myod1) nucleus (Myod1) enzyme binding (Myod1)
DNA binding (Myod1) transcription factor binding (Myod1) cytoplasm (Myod1)
Anatomy Link Frequency
skeletal muscle 4
Myod1 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 3 34.88 Quite Low
Inflammation 28 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
Osteoarthritis 4 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Disease 98 98.00 Very High Very High Very High
Frailty 38 78.40 Quite High
Muscle Disease 29 76.32 Quite High
Atrophic Muscular Disorders 1 75.20 Quite High
Targeted Disruption 3 67.68 Quite High
Muscular Atrophy 5 58.24 Quite High
Apoptosis 16 50.72 Quite High
Tendinopathy 5 50.00 Quite Low
Stress 33 41.32 Quite Low
Obesity 2 18.28 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression levels of these marker genes confirmed the accuracy of the dissection protocol since the relative levels of Myod1 expression in the Achilles tendon and spinal ligament were negligible as was the expression of Col2a1 in the skeletal muscle.
Regulation (levels) of Gene_expression (expression) of Myod1 in skeletal muscle
1) Confidence 0.41 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2792148 Disease Relevance 0.08 Pain Relevance 0
No studies have so far investigated whether alterations in MyoD and Id expression also occur in skeletal muscle from patients with COPD and whether they also suffer from an impaired skeletal muscle regenerative capacity.


Spec (whether) Regulation (alterations) of Gene_expression (expression) of MyoD in skeletal muscle associated with pulmonary disease
2) Confidence 0.16 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2695204 Disease Relevance 0.62 Pain Relevance 0

General Comments

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