INT272972

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 6
Disease Relevance 1.21
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (ADAMTS2) extracellular region (ADAMTS2) proteinaceous extracellular matrix (ADAMTS2)
Anatomy Link Frequency
blood 1
Sertoli cells 1
ADAMTS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 5 35.36 Quite Low
Glutamate 7 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
ketamine 5 5.00 Very Low Very Low Very Low
anesthesia 5 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
nMDA receptor 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Serotonin 2 5.00 Very Low Very Low Very Low
Glutamate receptor 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 61 96.24 Very High Very High Very High
Disease 78 91.40 High High
Cognitive Disorder 24 81.60 Quite High
Hyperinsulinism 5 79.52 Quite High
Hyperglycemia 20 76.72 Quite High
Aggression 6 31.84 Quite Low
Hallucination 4 29.84 Quite Low
Adhesions 15 27.12 Quite Low
Dementia 7 5.00 Very Low Very Low Very Low
Aging 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Currently, a major hurdle to use NPI for xenograft is the delay in achieving the posttransplant normalization of blood glucose in diabetic recipients.
Regulation (use) of NPI in blood associated with diabetes mellitus
1) Confidence 0.02 Published 2010 Journal Stem Cells International Section Body Doc Link PMC2956457 Disease Relevance 0.43 Pain Relevance 0
Effects of Encapsulated Sertoli Cells on NPI Cell Monolayers: Assessment of Differentiation Markers by Real Time PCR (qPCR)
Regulation (Effects) of NPI
2) Confidence 0.02 Published 2010 Journal Stem Cells International Section Body Doc Link PMC2956457 Disease Relevance 0 Pain Relevance 0
Effects of Encapsulated Sertoli Cells on NPI Cell Monolayers: Evaluation of Differentiation Markers by Immunohistochemistry
Regulation (Effects) of NPI
3) Confidence 0.02 Published 2010 Journal Stem Cells International Section Body Doc Link PMC2956457 Disease Relevance 0.08 Pain Relevance 0
In this respect, we had previously shown that coincubation of NPI with Sertoli cells (SCs) induced rapid and significant maturation and differentiation of NPI immature into functionally competent, mature ?
Regulation (differentiation) of NPI in Sertoli cells
4) Confidence 0.02 Published 2010 Journal Stem Cells International Section Body Doc Link PMC2956457 Disease Relevance 0.25 Pain Relevance 0
Effects of Encapsulated Sertoli Cells on NPI Cell Monolayers: Evaluation of Differentiation Markers by Western Blot Analysis
Regulation (Effects) of NPI
5) Confidence 0.02 Published 2010 Journal Stem Cells International Section Body Doc Link PMC2956457 Disease Relevance 0 Pain Relevance 0
As is shown in Table 1, memantine showed a statistically significant effect on the NPI in only 2 studies.
Regulation (effect) of NPI
6) Confidence 0.01 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695219 Disease Relevance 0.45 Pain Relevance 0

General Comments

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