INT272984

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Context Info
Confidence 0.24
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.78
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6) extracellular region (Il6) cell adhesion (Itgam)
nucleus (Itgam)
Anatomy Link Frequency
hippocampus 4
Il6 (Mus musculus)
Itgam (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 28 99.48 Very High Very High Very High
cytokine 150 93.32 High High
Central nervous system 12 83.20 Quite High
Inflammation 20 5.00 Very Low Very Low Very Low
depression 18 5.00 Very Low Very Low Very Low
antidepressant 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
long-term potentiation 2 5.00 Very Low Very Low Very Low
fluoxetine 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperplasia 38 100.00 Very High Very High Very High
Neurodegenerative Disease 62 66.80 Quite High
Targeted Disruption 8 65.04 Quite High
Apoptosis 4 10.52 Low Low
Injury 2 6.48 Low Low
INFLAMMATION 22 5.00 Very Low Very Low Very Low
Depression 20 5.00 Very Low Very Low Very Low
Cancer 6 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low
Cognitive Disorder 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is possible that IL-6 may have promoted cellular proliferation by enhancing the production of growth factors from microglia or astrocytes,44 particularly given that IL-6 elevated expression of the microglial marker, CD11b, within the hippocampus.
IL-6 Positive_regulation (enhancing) of Gene_expression (expression) of CD11b in hippocampus associated with hippocampus and hyperplasia
1) Confidence 0.24 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695223 Disease Relevance 0.39 Pain Relevance 0.50
It is possible that IL-6 may have promoted cellular proliferation by enhancing the production of growth factors from microglia or astrocytes,44 particularly given that IL-6 elevated expression of the microglial marker, CD11b, within the hippocampus.
IL-6 Positive_regulation (elevated) of Gene_expression (expression) of CD11b in hippocampus associated with hippocampus and hyperplasia
2) Confidence 0.22 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695223 Disease Relevance 0.38 Pain Relevance 0.45

General Comments

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