INT272997

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL33) extracellular region (IL33) small molecule metabolic process (CYP3A4)
oxidoreductase activity (CYP3A4) endoplasmic reticulum (CYP3A4) enzyme binding (CYP3A4)
CYP3A4 (Homo sapiens)
IL33 (Homo sapiens)
Pain Link Frequency Relevance Heat
Desipramine 3 90.84 High High
Duloxetine 12 88.72 High High
Bioavailability 1 60.68 Quite High
Pain 6 27.12 Quite Low
Neurotransmitter 1 24.72 Low Low
Dopamine 3 19.80 Low Low
sSRI 14 5.00 Very Low Very Low Very Low
depression 14 5.00 Very Low Very Low Very Low
sNRI 13 5.00 Very Low Very Low Very Low
antidepressant 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Chronic Renal Failure 1 28.96 Quite Low
Pain 6 27.12 Quite Low
Disorders Of Creatine Metabolism 1 18.32 Low Low
Depression 42 5.00 Very Low Very Low Very Low
Vomiting 10 5.00 Very Low Very Low Very Low
Anxiety Disorder 9 5.00 Very Low Very Low Very Low
Recurrence 7 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 6 5.00 Very Low Very Low Very Low
Sleep Disorders 5 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
DVS is primarily metabolized by conjugation and, to a minor extent, through CYP3A4 mediated oxidative metabolism.
CYP3A4 Binding (metabolized) of DVS
1) Confidence 0.03 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695227 Disease Relevance 0 Pain Relevance 0.25

General Comments

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