INT273000

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.45
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.77
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL33) extracellular region (IL33)
Anatomy Link Frequency
plasma 1
groove 1
eosinophil 1
urine 1
IL33 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bioavailability 2 96.64 Very High Very High Very High
Inflammatory response 2 87.96 High High
Duloxetine 24 68.48 Quite High
Desipramine 6 65.20 Quite High
Inflammation 27 64.32 Quite High
Pain 12 63.08 Quite High
Neurotransmitter 2 60.68 Quite High
chemokine 6 58.80 Quite High
Dopamine 6 55.76 Quite High
Serotonin 8 35.08 Quite Low
Disease Link Frequency Relevance Heat
Shock 2 93.88 High High
Gastroenteritis 10 90.96 High High
Viral Infection 9 87.68 High High
INFLAMMATION 29 87.60 High High
Rhinitis 62 87.08 High High
Asthma 19 83.12 Quite High
Chronic Renal Failure 2 83.04 Quite High
Eczema 31 79.48 Quite High
Anaphylaxis 1 73.84 Quite High
Disorders Of Creatine Metabolism 2 72.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This receptor-ligand pair may contribute to both innate and acquired Alternaria-induced eosinophil responses of the airways via Alternaria-induced IL33 release from airway epithelial cells (H.
Localization (release) of IL33 in eosinophil
1) Confidence 0.45 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2897889 Disease Relevance 1.02 Pain Relevance 0.13
DVS sustained release was considered safe in healthy volunteers up to a single dose of 750 mg27 and was well tolerated in multiple doses up to 450 mg.28 The plasma protein binding of DVS is low (30%) and is independent of drug concentration.
Localization (release) of DVS in plasma
2) Confidence 0.13 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695227 Disease Relevance 0.06 Pain Relevance 0.29
Since DVS is almost entirely excreted in urine, patients with renal impairment present a greater clinical concern.
Localization (excreted) of DVS in urine
3) Confidence 0.11 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695227 Disease Relevance 0.16 Pain Relevance 0.14
Dimerization of E2 and HEV neutralization
Localization (neutralization) of HEV
4) Confidence 0.05 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2714988 Disease Relevance 0.28 Pain Relevance 0
Hence we propose that the dimeric form of E2 is essential to position these groove regions for the neutralization of HEV.
Localization (neutralization) of HEV in groove
5) Confidence 0.05 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2714988 Disease Relevance 0.25 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox