INT273020

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Context Info
Confidence 0.22
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (FGF9, PDE11A) cytoplasm (FGF9, PDE11A) cytosol (PDE11A)
extracellular space (FGF9) extracellular region (FGF9) cellular_component (PDE11A)
FGF9 (Homo sapiens)
PDE11A (Homo sapiens)
Pain Link Frequency Relevance Heat
antidepressant 17 100.00 Very High Very High Very High
depression 8 50.00 Quite Low
Desipramine 5 5.00 Very Low Very Low Very Low
fluoxetine 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 44 99.62 Very High Very High Very High
Hyperplasia 1 34.40 Quite Low
Pituitary Acth Hypersecretion 1 33.16 Quite Low
Cancer 2 22.68 Low Low
Pituitary Cancer 1 8.32 Low Low
Attention Deficit Hyperactivity Disorder 1 5.00 Very Low Very Low Very Low
Mental Disorders 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The PDE11A and PDE1A genes have been included in the study because (1) they are located within 2q31–35, (2) as we indicated previously, the PDE11A individual haplotype is associated with MDD and three SNPs on PDE11A and PDE1A are associated with antidepressant drug response,12 and (3) the PDE11A gene has the GAF domain.
GAF Binding (associated) of PDE11A associated with antidepressant and depression
1) Confidence 0.22 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695232 Disease Relevance 0.30 Pain Relevance 0.11

General Comments

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