INT273024

Context Info Confidence 0.04 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.24 Pain Relevance 0.21

plasma membrane (FXYD1)

Anatomy Link Frequency legs 1 FXYD1 (Homo sapiens) RLS (Homo sapiens)

Pain Link Frequency Relevance Heat anticonvulsant 1 88.60 Pain 10 83.44 Dopamine 19 5.00 agonist 19 5.00 peripheral neuropathy 8 5.00 transdermal 6 5.00 Bioavailability 4 5.00 Eae 3 5.00 withdrawal 2 5.00 Gabapentin 2 5.00

Disease Link Frequency Relevance Heat Restless Legs Syndrome 168 100.00 Akathisia 16 98.56 Sleep Disorders 25 98.16 Pain 3 83.44 Sleep-wake Transition Disorders 1 81.92 Myoclonus 1 75.56 Cramps 2 61.76 Anxiety Disorder 1 57.44 Hypotension 2 50.08 Syndrome 2 46.16

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Differently from individuals suffering from PLM associated to RLS, these patients do not complain of restlessness or disagreeable sensations in the legs.

PLM Binding (associated) of RLS in legs associated with akathisia and restless legs syndrome

1) Confidence 0.04 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695234 Disease Relevance 1.24 Pain Relevance 0.21

General Comments

This test has worked.