INT273038

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.08
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.26
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Vtn) extracellular region (Vtn) cell adhesion (Vtn)
proteinaceous extracellular matrix (Vtn) extracellular matrix organization (Vtn)
Anatomy Link Frequency
B cell 1
Vtn (Mus musculus)
Pain Link Frequency Relevance Heat
Multiple sclerosis 68 96.28 Very High Very High Very High
Neuropeptide 26 91.56 High High
Spinal cord 39 84.88 Quite High
Inflammation 67 84.80 Quite High
Central nervous system 81 81.92 Quite High
Demyelination 123 80.84 Quite High
cytokine 8 80.40 Quite High
spinal inflammation 2 66.60 Quite High
Neuritis 19 5.00 Very Low Very Low Very Low
Substantia nigra 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Disease 30 99.98 Very High Very High Very High
Multiple Sclerosis 75 96.28 Very High Very High Very High
Fatigue 22 95.40 Very High Very High Very High
INFLAMMATION 81 93.68 High High
Syndrome 4 91.36 High High
Sprains And Strains 83 88.24 High High
Demyelinating Disease 229 80.84 Quite High
Disease 58 77.48 Quite High
Viral Meningitis 14 73.40 Quite High
Cancer 3 72.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However autoimmunity directed at VN guanine nucleotide protein-coupled receptors (GPCRs) is currently unproven and loss-of-function autoimmunity to GPCRs generally is not well documented,22 although parallels exist with other conditions eg, Sjogren’s syndrome which has T cell and/or B cell antibody targeting of acetylcholine GPCRs.37
Regulation (directed) of VN in B cell associated with autoimmune disease and syndrome
1) Confidence 0.08 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695238 Disease Relevance 1.04 Pain Relevance 0.46
Hence effects of VN autoimmunity may extend beyond the BBB and BSB and a complex multisystem explanation for certain neuropsychiatric fatigue-related conditions is possible.
Regulation (effects) of VN associated with autoimmune disease and fatigue
2) Confidence 0.07 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695238 Disease Relevance 0.72 Pain Relevance 0.23
As alteration of the MHV S protein influences pathogenesis, it is important to understand how alteration of the S protein alters the virus-host interaction.
Regulation (alteration) of S protein
3) Confidence 0.03 Published 2010 Journal Interdisciplinary Perspectives on Infectious Diseases Section Body Doc Link PMC2905936 Disease Relevance 0.50 Pain Relevance 0.23

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox