INT273045

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Context Info
Confidence 0.17
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Vip, Adcyap1) signal transduction (Adcyap1) extracellular space (Adcyap1)
Vip (Mus musculus)
Adcyap1 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 23 99.84 Very High Very High Very High
Spinal cord 3 97.60 Very High Very High Very High
Neuropeptide 13 96.12 Very High Very High Very High
Inflammation 12 60.36 Quite High
cytokine 2 44.08 Quite Low
Multiple sclerosis 23 5.00 Very Low Very Low Very Low
Substantia nigra 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Disease 15 97.00 Very High Very High Very High
Hypoxia 3 82.52 Quite High
INFLAMMATION 19 77.20 Quite High
Fatigue 11 53.04 Quite High
Cancer 1 34.32 Quite Low
Necrosis 1 33.84 Quite Low
Injury 3 27.32 Quite Low
Multiple Sclerosis 28 5.00 Very Low Very Low Very Low
Disease 23 5.00 Very Low Very Low Very Low
Motor Neuron Diseases 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present paper asserts that, in view of the many vital roles of PACAP and VIP in CNS neuroregulatory and immunological function including BBB function, autoimmunity to these VNs or their receptors will have significant effects on homeostasis possibly resulting in neuropsychiatric symptoms.


VIP Regulation (roles) of PACAP associated with autoimmune disease, neuropeptide and central nervous system
1) Confidence 0.17 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695238 Disease Relevance 0.50 Pain Relevance 0.38

General Comments

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