INT273068

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (P2RY2) aging (P2RY2) protein complex assembly (TFAP4)
DNA binding (TFAP4) embryo development (P2RY2) signal transducer activity (P2RY2)
P2RY2 (Homo sapiens)
TFAP4 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 3 99.40 Very High Very High Very High
antagonist 5 17.08 Low Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 44 97.64 Very High Very High Very High
Toxicity 1 76.56 Quite High
Wound Healing 23 45.12 Quite Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Infection 2 5.00 Very Low Very Low Very Low
Burns 1 5.00 Very Low Very Low Very Low
Cataract 1 5.00 Very Low Very Low Very Low
Eye Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As with many other agonists (for example, insulin), when Ap4A binds to its receptor, P2Y2-R, on the surface of a cell, the Ap4A-P2Y2-R complex undergoes endocytosis and is subsequently attacked by intracellular lysosomal enzymes.
P2Y2-R Binding (binds) of Ap4A associated with agonist
1) Confidence 0.01 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2695252 Disease Relevance 0.27 Pain Relevance 0.05

General Comments

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