INT273079

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Context Info
Confidence 0.59
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.52
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (P2RY2) aging (P2RY2) plasma membrane (P2RY2)
embryo development (P2RY2) lysosome (P2RY2) signal transducer activity (P2RY2)
Anatomy Link Frequency
corneas 2
P2RY2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 6 95.56 Very High Very High Very High
agonist 9 84.88 Quite High
antagonist 15 42.56 Quite Low
anesthesia 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cataract 3 95.96 Very High Very High Very High
INFLAMMATION 6 95.56 Very High Very High Very High
Injury 132 82.16 Quite High
Wound Healing 69 58.64 Quite High
Infection 6 5.00 Very Low Very Low Very Low
Burns 3 5.00 Very Low Very Low Very Low
Toxicity 3 5.00 Very Low Very Low Very Low
Eye Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inhibition of P2Y2-R expression by siRNA
Negative_regulation (Inhibition) of Gene_expression (expression) of P2Y2-R
1) Confidence 0.59 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2695252 Disease Relevance 0.19 Pain Relevance 0.05
Clear reduction of P2Y2-R expression was observed at both the mRNA and protein levels in corneas treated with siRNA.
Negative_regulation (reduction) of Gene_expression (expression) of P2Y2-R in corneas
2) Confidence 0.43 Published 2009 Journal Molecular Vision Section Abstract Doc Link PMC2695252 Disease Relevance 0.27 Pain Relevance 0.04
These data indicate that the P2Y2-R levels were significantly reduced to approximately 32% of control levels by P2Y2-R siRNA #2.
Negative_regulation (reduced) of Gene_expression (levels) of P2Y2-R
3) Confidence 0.43 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2695252 Disease Relevance 0.06 Pain Relevance 0

General Comments

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