INT27309

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Context Info
Confidence 0.57
First Reported 1989
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.30
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Mbp)
Anatomy Link Frequency
platelet 2
optic nerve 2
Mbp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 3 98.44 Very High Very High Very High
anesthesia 2 25.00 Low Low
Demyelination 1 8.48 Low Low
Inflammation 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 6 91.96 High High
Blindness 4 81.68 Quite High
Ganglion Cysts 25 76.68 Quite High
Optic Disorders 28 50.00 Quite Low
Demyelinating Disease 1 8.48 Low Low
Disease 9 5.00 Very Low Very Low Very Low
Apoptosis 5 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Frailty 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intravenous injection of the specific platelet-activating factor (PAF) antagonist BN 52021 (10 mg/kg), 30 min before bupivacaine administration (2 mg/kg i.v.) suppressed both the decrease of MBP and HR.
Negative_regulation (suppressed) of Negative_regulation (decrease) of MBP in platelet associated with antagonist
1) Confidence 0.57 Published 1989 Journal Pharmacol. Res. Section Abstract Doc Link 2594614 Disease Relevance 0.09 Pain Relevance 0.09
Also, the rotenone exposure for 2 months resulted in a reduction of myelin basic protein (MBP) in the optic nerve by approximately 20% of control (Figure 4).
Negative_regulation (resulted) of Negative_regulation (reduction) of myelin basic protein in optic nerve
2) Confidence 0.36 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2900204 Disease Relevance 0.21 Pain Relevance 0

General Comments

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