INT273096

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Mtor, Grip2) cytoplasm (Mtor, Grip2) mitochondrion (Mtor)
Golgi apparatus (Mtor) cytosol (Mtor) plasma membrane (Grip2)
Anatomy Link Frequency
hippocampus 2
Mtor (Rattus norvegicus)
Grip2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hippocampus 25 98.48 Very High Very High Very High
long-term potentiation 9 5.00 Very Low Very Low Very Low
Glutamate receptor 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
amygdala 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 2 65.04 Quite High
Shock 4 5.00 Very Low Very Low Very Low
Amnesia 3 5.00 Very Low Very Low Very Low
Decapitation 2 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Aging 1 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here we show that consolidation of inhibitory avoidance (IA) LTM entails mTOR activation in the dorsal hippocampus at the moment of and 3 h after training and is associated with a rapid and rapamycin-sensitive increase in AMPA receptor GluR1 subunit expression, which was also blocked by intra-hippocampal delivery of GluR1 antisense oligonucleotides (ASO).
rapamycin Positive_regulation (increase) of Gene_expression (expression) of AMPA receptor in hippocampus associated with hippocampus
1) Confidence 0.05 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2695538 Disease Relevance 0.07 Pain Relevance 0.05

General Comments

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