INT273111

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Context Info
Confidence 0.44
First Reported 2009
Last Reported 2009
Negated 0
Speculated 2
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.07
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Mtor) Golgi apparatus (Mtor) endoplasmic reticulum (Mtor)
cytoplasm (Mtor) cytosol (Mtor) extracellular region (Bdnf)
Bdnf (Rattus norvegicus)
Mtor (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hippocampus 75 91.56 High High
long-term potentiation 27 84.64 Quite High
Glutamate receptor 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
amygdala 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 12 73.24 Quite High
Amnesia 9 5.00 Very Low Very Low Very Low
Decapitation 6 5.00 Very Low Very Low Very Low
Anxiety Disorder 6 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Aging 3 5.00 Very Low Very Low Very Low
Toxicity 3 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We began to answer these questions by examining whether BDNF triggers the activation of mTOR induced by IA training.
BDNF Spec (whether) Positive_regulation (triggers) of Spec (whether) Positive_regulation (induced) of mTOR
1) Confidence 0.44 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2695538 Disease Relevance 0 Pain Relevance 0.11
We began to answer these questions by examining whether BDNF triggers the activation of mTOR induced by IA training.
BDNF Spec (whether) Positive_regulation (triggers) of Spec (whether) Positive_regulation (activation) of mTOR
2) Confidence 0.44 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2695538 Disease Relevance 0 Pain Relevance 0.11
Our findings are consistent with others showing that, in vitro, BDNF upregulates local translation of PSD95 through mTOR pathway [76] and enhances the expression of GluR1 subunit of AMPA receptors via activation of mTOR [48].
BDNF Positive_regulation (enhances) of Positive_regulation (activation) of mTOR
3) Confidence 0.44 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2695538 Disease Relevance 0.07 Pain Relevance 0.19

General Comments

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