INT273132

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Context Info
Confidence 0.31
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 1.28
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (FDPS) mitochondrion (FDPS) small molecule metabolic process (FDPS)
nucleolus (FDPS) nucleus (FDPS) cytoplasm (FDPS)
FDPS (Homo sapiens)
Pain Link Frequency Relevance Heat
pregabalin 156 96.80 Very High Very High Very High
Central nervous system 8 5.00 Very Low Very Low Very Low
Pain 8 5.00 Very Low Very Low Very Low
gABA 8 5.00 Very Low Very Low Very Low
Neurobehavioral 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
Calcium channel 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 164 98.96 Very High Very High Very High
Anxiety Disorder 556 95.16 Very High Very High Very High
Sleep Disorders 60 94.68 High High
Stress 12 5.00 Very Low Very Low Very Low
Generalized Anxiety Disorder 4 5.00 Very Low Very Low Very Low
Bradycardia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To test drug effects on FPS during the unpredictable shock context, a Context (Neutral context, Unpredictable context) × Drug (4) ANOVA was employed.
Regulation (effects) of FPS associated with shock
1) Confidence 0.31 Published 2009 Journal Psychopharmacology (Berl) Section Body Doc Link PMC2695548 Disease Relevance 0.26 Pain Relevance 0
In our previous work, even though the drug manipulations did not affect FPS significantly, variation in baseline startle between drug conditions correlated significantly with differences in state anxiety and sedation as a result of drug administration (Baas et al. 2002a).
Neg (not) Regulation (affect) of FPS associated with anxiety disorder and sleep disorders
2) Confidence 0.19 Published 2009 Journal Psychopharmacology (Berl) Section Body Doc Link PMC2695548 Disease Relevance 0.54 Pain Relevance 0
First, the lack of significant effects of alprazolam on context-specific FPS could be a false negative.
Regulation (effects) of FPS
3) Confidence 0.19 Published 2009 Journal Psychopharmacology (Berl) Section Body Doc Link PMC2695548 Disease Relevance 0.17 Pain Relevance 0.12
Analyses on T scores revealed highly significant effects of cued FPS (F(1,19;GG??
Regulation (effects) of FPS
4) Confidence 0.19 Published 2009 Journal Psychopharmacology (Berl) Section Body Doc Link PMC2695548 Disease Relevance 0.32 Pain Relevance 0.22

General Comments

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