INT273155

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Context Info
Confidence 0.53
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.74
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (COL8A2) proteinaceous extracellular matrix (COL8A2) protein binding, bridging (COL8A2)
extracellular matrix organization (COL8A2)
COL8A2 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 6 53.60 Quite High
Pain 15 5.00 Very Low Very Low Very Low
Inflammation 9 5.00 Very Low Very Low Very Low
peripheral neuropathy 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Corneal Disease 27 72.08 Quite High
Pressure And Volume Under Development 33 62.96 Quite High
Corneal Edema 18 56.36 Quite High
Fibrosis 9 53.60 Quite High
Cataract 12 52.80 Quite High
Keratitis 9 43.20 Quite Low
Corneal Neovascularization 3 42.08 Quite Low
Disease 75 5.00 Very Low Very Low Very Low
Congenital Anomalies 63 5.00 Very Low Very Low Very Low
Corneal Opacity 45 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For reasons that remain to be determined, FECD is expressed much more frequently in females.
Gene_expression (expressed) of FECD
1) Confidence 0.53 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2695576 Disease Relevance 0.19 Pain Relevance 0
Leu450Trp mutant in COL8A2 has also been found in early-onset FECD [127].
Gene_expression (found) of COL8A2
2) Confidence 0.47 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2695576 Disease Relevance 0.27 Pain Relevance 0.03
Leu450Trp mutant in COL8A2 has also been found in early-onset FECD [127].
Gene_expression (found) of FECD
3) Confidence 0.41 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2695576 Disease Relevance 0.28 Pain Relevance 0.03

General Comments

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