INT273176

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.63
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Elane) molecular_function (Elane) cellular_component (Elane)
biological_process (Elane) cytoplasm (Elane)
Anatomy Link Frequency
neutrophil 2
Elane (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 29 91.96 High High
Potency 1 72.40 Quite High
cytokine 8 72.32 Quite High
adenocard 2 57.64 Quite High
chemokine 3 45.92 Quite Low
Inflammatory mediators 2 45.00 Quite Low
cINOD 8 35.52 Quite Low
fibrosis 6 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 1 94.56 High High
Pulmonary Disease 55 93.16 High High
INFLAMMATION 40 91.96 High High
Disease 18 48.04 Quite Low
Nicotine Addiction 10 5.00 Very Low Very Low Very Low
Vomiting 9 5.00 Very Low Very Low Very Low
Emphysema 8 5.00 Very Low Very Low Very Low
Fibrosis 6 5.00 Very Low Very Low Very Low
Asthma 5 5.00 Very Low Very Low Very Low
Diarrhoea 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, PDE4 inhibitors like roflumilast (Figure 1) suppressed a variety of functions ascribed to neutrophils including protease (neutrophil elastase, matrix metalloprotease 9) and myeloperoxidase release (Jones et al 2005); oxygen radical production (Hatzelmann and Schudt 2001); and adhesion to endothelial cells (Jones et al 2005) by inhibiting the expression of ?
Positive_regulation (ascribed) of Gene_expression (protease) of neutrophil elastase in neutrophil associated with adhesions
1) Confidence 0.04 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2695611 Disease Relevance 0.63 Pain Relevance 0.26

General Comments

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