INT273232

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Context Info
Confidence 0.28
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 3.16
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

embryo development (Cdk5, Cdk5r1) cytoplasm (Cdk5, Cdk5r1) nucleus (Cdk5, Cdk5r1)
plasma membrane (Cdk5, Cdk5r1) cell cycle (Cdk5, Cdk5r1) kinase activity (Cdk5, Cdk5r1)
Cdk5 (Mus musculus)
Cdk5r1 (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 12 92.96 High High
Neuronal excitability 34 85.12 High High
medulla 4 55.52 Quite High
depression 16 19.36 Low Low
antagonist 10 5.00 Very Low Very Low Very Low
hyperexcitability 6 5.00 Very Low Very Low Very Low
anticonvulsant 6 5.00 Very Low Very Low Very Low
tetrodotoxin 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sclerosis 4 97.20 Very High Very High Very High
Targeted Disruption 154 93.76 High High
Shock 20 90.12 High High
Status Epilepticus 14 89.00 High High
Epilepsy 32 88.16 High High
Convulsion 136 87.68 High High
Death 8 81.52 Quite High
Depression 16 19.36 Low Low
Anaerobic Bacterial Infections 16 5.00 Very Low Very Low Very Low
Malformations Of Cortical Development 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There may be common mechanistic features between loss of Cdk5 and diversion of Cdk5 to form a complex with p25.
Negative_regulation (loss) of Cdk5 Binding (form) of p25
1) Confidence 0.28 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2695674 Disease Relevance 1.58 Pain Relevance 0.12
There may be common mechanistic features between loss of Cdk5 and diversion of Cdk5 to form a complex with p25.
Negative_regulation (loss) of Cdk5 Binding (complex) of p25
2) Confidence 0.28 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2695674 Disease Relevance 1.58 Pain Relevance 0.12

General Comments

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