INT273236

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Context Info
Confidence 0.13
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Cdk5, Car2) cytosol (Cdk5, Car2) lyase activity (Car2)
embryo development (Cdk5) extracellular space (Car2) nucleocytoplasmic transport (Cdk5)
Anatomy Link Frequency
vesicles 1
Cdk5 (Mus musculus)
Car2 (Mus musculus)
Pain Link Frequency Relevance Heat
depression 8 98.12 Very High Very High Very High
Neurotransmitter 1 54.68 Quite High
Neuronal excitability 17 51.00 Quite High
Hippocampus 6 17.44 Low Low
antagonist 5 5.00 Very Low Very Low Very Low
hyperexcitability 3 5.00 Very Low Very Low Very Low
anticonvulsant 3 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
tetrodotoxin 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 8 98.12 Very High Very High Very High
Targeted Disruption 77 97.20 Very High Very High Very High
Convulsion 68 46.60 Quite Low
Shock 10 5.28 Low Low
Epilepsy 16 5.00 Very Low Very Low Very Low
Anaerobic Bacterial Infections 8 5.00 Very Low Very Low Very Low
Status Epilepticus 7 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Malformations Of Cortical Development 2 5.00 Very Low Very Low Very Low
Anxiety Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cdk5 may theoretically confer these changes by increasing the number of presynaptic vesicles, increasing presynaptic Ca2+-influx, or increasing sensitivity to presynaptic Ca2+.
Cdk5 Positive_regulation (increasing) of Ca2 in vesicles
1) Confidence 0.13 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2695674 Disease Relevance 0.45 Pain Relevance 0.10

General Comments

This test has worked.

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