INT273238

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Context Info
Confidence 0.07
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

phosphatase activity (Ptprs) transport (Grin1) cell adhesion (Ptprs)
plasma membrane (Grin1) enzyme binding (Grin1) cytoplasm (Grin1)
Grin1 (Mus musculus)
Ptprs (Mus musculus)
Pain Link Frequency Relevance Heat
depression 8 85.12 High High
Neurotransmitter 1 65.84 Quite High
Neuronal excitability 17 62.16 Quite High
Hippocampus 6 28.60 Quite Low
antagonist 5 5.00 Very Low Very Low Very Low
hyperexcitability 3 5.00 Very Low Very Low Very Low
anticonvulsant 3 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
tetrodotoxin 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 77 95.12 Very High Very High Very High
Depression 8 85.12 High High
Convulsion 68 57.76 Quite High
Shock 10 16.44 Low Low
Epilepsy 16 5.00 Very Low Very Low Very Low
Anaerobic Bacterial Infections 8 5.00 Very Low Very Low Very Low
Status Epilepticus 7 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Malformations Of Cortical Development 2 5.00 Very Low Very Low Very Low
Anxiety Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
During the detailed LTP analyses, we find that loss of Cdk5 also leads to an NMDAR-independent enhancement in PTP, a presynaptic form of short-term plasticity.
NMDAR Neg (independent) Positive_regulation (enhancement) of PTP
1) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2695674 Disease Relevance 0.51 Pain Relevance 0.14

General Comments

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