INT273328

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Context Info
Confidence 0.07
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.38
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mmp9) extracellular space (Mmp9) extracellular region (Mmp9)
proteinaceous extracellular matrix (Mmp9) extracellular matrix organization (Mmp9) protein complex (Mmp9)
Anatomy Link Frequency
neutrophil 2
Mmp9 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 31 90.16 High High
Inflammatory response 4 79.84 Quite High
Inflammatory marker 4 33.16 Quite Low
Potency 5 30.92 Quite Low
chemokine 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 33 90.16 High High
Targeted Disruption 5 85.08 High High
Pulmonary Disease 19 56.88 Quite High
Pneumonia 7 50.00 Quite Low
Asthma 4 16.16 Low Low
Vomiting 3 5.00 Very Low Very Low Very Low
Emphysema 3 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 2 5.00 Very Low Very Low Very Low
Exsanguination 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the acute smoke exposure protocol used here (1-week model), orally delivered roflumilast at 5 mg/kg/day partially reduced neutrophil recruitment (20% reduction), but statistical significance could not be reached, and had no effect on KC or pro-MMP-9 secretion (Figure 6).
Neg (no) Regulation (effect) of Localization (secretion) of MMP-9 in neutrophil
1) Confidence 0.07 Published 2009 Journal Respir Res Section Body Doc Link PMC2696437 Disease Relevance 0.38 Pain Relevance 0.12

General Comments

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