INT273352

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Context Info
Confidence 0.43
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pde4b) signal transduction (Pde7a) nucleus (Pde4b)
cytoplasm (Pde4b)
Pde7a (Mus musculus)
Pde4b (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 31 92.08 High High
Inflammatory response 4 84.56 Quite High
chemokine 4 66.68 Quite High
Inflammatory mediators 1 44.40 Quite Low
Potency 5 5.00 Very Low Very Low Very Low
Inflammatory marker 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 5 95.96 Very High Very High Very High
Pneumonia 7 92.08 High High
INFLAMMATION 33 84.56 Quite High
Pulmonary Disease 19 81.84 Quite High
Asthma 4 5.00 Very Low Very Low Very Low
Vomiting 3 5.00 Very Low Very Low Very Low
Emphysema 3 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 2 5.00 Very Low Very Low Very Low
Exsanguination 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One lead sequence specific for both mouse PDE4B and 4D mRNAs (AON 4B/4D), and one for mouse PDE7A (AON 7A) were selected, as well as control sequences, and used for all in vivo experiments.
PDE7A Positive_regulation (one) of Localization (specific) of PDE4B
1) Confidence 0.43 Published 2009 Journal Respir Res Section Body Doc Link PMC2696437 Disease Relevance 0.68 Pain Relevance 0.24

General Comments

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