INT273353

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Context Info
Confidence 0.26
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Twist1) signal transduction (Pde4d) Golgi apparatus (Pde4d)
nucleus (Twist1) plasma membrane (Pde4d) cytoskeleton (Pde4d)
Anatomy Link Frequency
epithelial cells 2
Pde4d (Mus musculus)
Twist1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 4 99.36 Very High Very High Very High
Inflammation 31 50.00 Quite Low
chemokine 4 33.20 Quite Low
cytokine 2 32.60 Quite Low
Inflammatory mediators 1 31.20 Quite Low
Potency 5 5.00 Very Low Very Low Very Low
Inflammatory marker 4 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Disease 19 99.52 Very High Very High Very High
INFLAMMATION 33 99.18 Very High Very High Very High
Targeted Disruption 5 51.56 Quite High
Pneumonia 7 50.00 Quite Low
Asthma 4 5.00 Very Low Very Low Very Low
Vomiting 3 5.00 Very Low Very Low Very Low
Emphysema 3 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 2 5.00 Very Low Very Low Very Low
Exsanguination 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As epithelial cells lining the airways are believed to play a critical role in the modulation of the inflammatory response in COPD, we first assessed the effect of AON 4B/4D and AON 7A on PDE expression levels in NHBE cells.
4D Regulation (effect) of Gene_expression (expression) of PDE in epithelial cells associated with inflammatory response and pulmonary disease
1) Confidence 0.26 Published 2009 Journal Respir Res Section Body Doc Link PMC2696437 Disease Relevance 0.25 Pain Relevance 0.05

General Comments

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