INT273365

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (JAK2, SOCS1) cytosol (JAK2, SOCS1) nucleus (JAK2, SOCS1)
cell differentiation (JAK2) histone binding (JAK2) signal transduction (JAK2)
JAK2 (Homo sapiens)
SOCS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
withdrawal 2 64.52 Quite High
cytokine 5 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
local anesthetic 1 5.00 Very Low Very Low Very Low
Calcium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 11 39.24 Quite Low
Hypertrophy 9 28.60 Quite Low
Muscle Wasting Disease 1 12.08 Low Low
Appetite Loss 2 9.52 Low Low
Disease 2 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Muscular Atrophy 1 5.00 Very Low Very Low Very Low
Frailty 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low
Leukemia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, SOCS3 can also recruit ubiquitin-transferases, facilitating the ubiquitination of JAK2, targeting the JAK protein for proteosomal degradation [26], [50].
JAK2 Regulation (targeting) of JAK protein
1) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2696599 Disease Relevance 0 Pain Relevance 0.06

General Comments

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