INT273442

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Snap25) transport (Napa) vesicle-mediated transport (Napa)
plasma membrane (Snap25) cytoplasm (Snap25)
Snap25 (Rattus norvegicus)
Napa (Mus musculus)
Pain Link Frequency Relevance Heat
Neurotransmitter 18 43.04 Quite Low
Glutamate 30 5.00 Very Low Very Low Very Low
tetrodotoxin 3 5.00 Very Low Very Low Very Low
Multiple sclerosis 3 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
Pyramidal cell 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 3 5.28 Low Low
Targeted Disruption 9 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Shock 6 5.00 Very Low Very Low Very Low
Demyelinating Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, when we incorporated syntaxin/SNAP-25 into liposomes and tested SNARE assembly in the presence of a soluble part of synaptobrevin, sphingosine did not enhance the ability of this membrane-free synaptobrevin to form SNARE complex with syntaxin and SNAP-25 (Figure S4).
SNAP-25 Binding (complex) of SNARE
1) Confidence 0.05 Published 2009 Journal Neuron Section Body Doc Link PMC2697323 Disease Relevance 0 Pain Relevance 0
Therefore synaptobrevin's ability to engage syntaxin/SNAP-25 can be analyzed through the formation of SDS-resistant SNARE complexes.
SNAP-25 Binding (engage) of SNARE
2) Confidence 0.04 Published 2009 Journal Neuron Section Body Doc Link PMC2697323 Disease Relevance 0 Pain Relevance 0
In contrast, when we incorporated syntaxin/SNAP-25 into liposomes and tested SNARE assembly in the presence of a soluble part of synaptobrevin, sphingosine did not enhance the ability of this membrane-free synaptobrevin to form SNARE complex with syntaxin and SNAP-25 (Figure S4).
SNAP-25 Binding (complex) of SNARE
3) Confidence 0.03 Published 2009 Journal Neuron Section Body Doc Link PMC2697323 Disease Relevance 0 Pain Relevance 0

General Comments

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