INT273604

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Context Info
Confidence 0.12
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Cdkn2a) aging (Cdkn2a) DNA binding (Cdkn2a)
protein complex (Cdkn2a) cytoplasm (Cdkn2a) nucleolus (Cdkn2a)
Anatomy Link Frequency
tubule 2
Cdkn2a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 8 71.72 Quite High
Calcium channel 2 56.08 Quite High
dopamine receptor 1 38.80 Quite Low
Dopamine 4 28.16 Quite Low
Clonidine 1 17.12 Low Low
Disease Link Frequency Relevance Heat
Acute Renal Failure 16 100.00 Very High Very High Very High
Renal Failure 4 97.96 Very High Very High Very High
Volume Depletion And Dehydration 2 80.16 Quite High
Cv Unclassified Under Development 8 71.72 Quite High
Necrosis 1 68.04 Quite High
Chronic Renal Failure 2 50.20 Quite High
Stress 1 48.64 Quite Low
Renal Disease 3 44.00 Quite Low
Disorders Of Creatine Metabolism 6 34.32 Quite Low
Communicable Diseases 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The antioxidant N-acetylcysteine was found to have no effect in preventing ARF in cardiac patients,35 or in reducing the rate of renal failure in patients undergoing heart and/or aortic surgery.36–38 The renal function of on-pump CABG patients was improved by leukodepletion, which prevented tubule destruction,39 and infusion of sodium nitroprusside resulted in improved renal function in cardiac patients.40 As hydration prior to surgery has been found to prevent renal damage,41 our patients were infused with 1–2 L of normal saline to prevent confounding the effects of dehydration with those of allopurinol and vitamin E.
Neg (no) Regulation (effect) of Negative_regulation (preventing) of ARF in tubule associated with acute renal failure, renal failure and volume depletion and dehydration
1) Confidence 0.12 Published 2009 Journal Vascular Health and Risk Management Section Body Doc Link PMC2697583 Disease Relevance 0.68 Pain Relevance 0.09

General Comments

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