INT273628

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Context Info
Confidence 0.52
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 3.07
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (Lor) protein binding, bridging (Lor)
Anatomy Link Frequency
epidermis 1
Lor (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 84 97.24 Very High Very High Very High
Inflammatory mediators 6 70.60 Quite High
Inflammatory response 18 58.00 Quite High
cytokine 22 55.96 Quite High
fibrosis 2 41.68 Quite Low
cINOD 8 33.88 Quite Low
member 8 4 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
psoriasis 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Keratitis 60 100.00 Very High Very High Very High
Targeted Disruption 28 99.16 Very High Very High Very High
Recurrence 20 97.84 Very High Very High Very High
INFLAMMATION 108 97.24 Very High Very High Very High
Congenital Anomalies 22 87.60 High High
Corneal Neovascularization 4 86.96 High High
Apoptosis 4 84.84 Quite High
Herpes Virus Infection 2 83.44 Quite High
Disease 16 80.40 Quite High
Acanthosis 16 78.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the current study, valuable information is provided by the LOR alone groups in which the NF-?
Gene_expression (groups) of LOR
1) Confidence 0.52 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2697669 Disease Relevance 0.47 Pain Relevance 0
The ameliorated clinical lesion of HSK after LOR treatment was accompanied by a dramatic reduction in recurrence-induced activation of NF-?
Gene_expression (lesion) of LOR associated with keratitis and recurrence
2) Confidence 0.52 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2697669 Disease Relevance 1.66 Pain Relevance 0.35
Loricrin was expressed in the granular and cornified layers in mice of all genotypes, although the loricrin-positive part of the epidermis was thicker in K5-R1/R2 animals.
Gene_expression (expressed) of Loricrin in epidermis
3) Confidence 0.28 Published 2010 Journal The Journal of Cell Biology Section Body Doc Link PMC2845079 Disease Relevance 0.68 Pain Relevance 0
Expression of loricrin was enhanced in the knockout mice (Fig.
Gene_expression (Expression) of loricrin associated with targeted disruption
4) Confidence 0.28 Published 2010 Journal The Journal of Cell Biology Section Body Doc Link PMC2845079 Disease Relevance 0.25 Pain Relevance 0.03

General Comments

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