INT273642

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Context Info
Confidence 0.35
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.35
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Cxcr4) signal transduction (Cxcr4) cytoplasmic membrane-bounded vesicle (Cxcr4)
plasma membrane (Cxcr4) signal transducer activity (Cxcr4)
Cxcr4 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 11 95.44 Very High Very High Very High
Inflammation 4 86.24 High High
Hippocampus 35 49.76 Quite Low
Central nervous system 7 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
Versed 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 86.24 High High
Injury 28 67.64 Quite High
Thrombosis 2 63.76 Quite High
Convulsion 44 45.20 Quite Low
Status Epilepticus 19 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 12 5.00 Very Low Very Low Very Low
Epilepsy 8 5.00 Very Low Very Low Very Low
Age-related Macular Degeneration 5 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This was done either by blocking endogenous SDF-1, blocking BMC-associated CXCR4 or increasing locally SDF-1 [11,12,18,21,26].
Negative_regulation (blocking) of CXCR4 Binding (associated) of
1) Confidence 0.35 Published 2009 Journal Nephrology Dialysis Transplantation Section Body Doc Link PMC2698094 Disease Relevance 0.35 Pain Relevance 0.04
To determine whether CXCL12-induced migration is mediated via CXCR4 receptors, we blocked CXCR4 receptors with a small pharmacological inhibitor, AMD3100 [40].
Negative_regulation (blocked) of CXCR4 Binding (receptors) of
2) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3013129 Disease Relevance 0 Pain Relevance 0.08

General Comments

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