INT273653

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Context Info
Confidence 0.08
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.21
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Cxcr4) transferase activity, transferring glycosyl groups (FUT1) Golgi apparatus (FUT1)
carbohydrate metabolic process (FUT1) signal transducer activity (Cxcr4) signal transduction (Cxcr4)
Anatomy Link Frequency
tail vein 2
Cxcr4 (Mus musculus)
FUT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 61.96 Quite High
imagery 2 57.88 Quite High
ischemia 4 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Versed 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 1 76.88 Quite High
Injury 25 71.72 Quite High
INFLAMMATION 2 61.96 Quite High
Cv Unclassified Under Development 4 5.00 Very Low Very Low Very Low
Acute Renal Failure 3 5.00 Very Low Very Low Very Low
Thrombosis 2 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Sepsis 1 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To validate whether anti-SDF-1 and anti-CXCR4 were also able to inhibit the migration of HSC in vivo, HSC were injected into the tail vein of naive mice with or without blocking either endogenous SDF-1 or HSC-associated CXCR4 with a monoclonal antibody as previously described [11,13,18,21].
CXCR4 Negative_regulation (inhibit) of HSC Binding (migration) of in tail vein
1) Confidence 0.08 Published 2009 Journal Nephrology Dialysis Transplantation Section Body Doc Link PMC2698094 Disease Relevance 0.21 Pain Relevance 0.06

General Comments

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