INT273657

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Context Info
Confidence 0.13
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.91
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Dss1 (Mus musculus)
Pain Link Frequency Relevance Heat
withdrawal 12 100.00 Very High Very High Very High
Kinase C 1 99.84 Very High Very High Very High
Inflammation 22 61.12 Quite High
cytokine 21 25.80 Quite Low
Inflammatory mediators 5 5.00 Very Low Very Low Very Low
Crohn's disease 4 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 7 93.20 High High
Colitis 28 87.64 High High
Body Weight 6 84.12 Quite High
Pressure And Volume Under Development 2 73.68 Quite High
Weight Loss 5 73.40 Quite High
Retinal Neovascularization 3 70.40 Quite High
Ulcers 2 68.72 Quite High
INFLAMMATION 26 61.12 Quite High
Diarrhoea 5 59.84 Quite High
Hemorrhage 2 51.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The reduction could be recovered after withdrawal of DSS, such as day 9 and day 14 groups.
Negative_regulation (recovered) of Negative_regulation (withdrawal) of DSS associated with withdrawal
1) Confidence 0.13 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2698136 Disease Relevance 0.84 Pain Relevance 0.24
This down-regulation of DSS and increased PSS was blocked by protein kinase C inhibition and SRPK1/2 inhibition.
Negative_regulation (blocked) of Negative_regulation (regulation) of DSS associated with kinase c
2) Confidence 0.05 Published 2010 Journal The Journal of Biological Chemistry Section Abstract Doc Link PMC2820781 Disease Relevance 0.07 Pain Relevance 0.05

General Comments

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